Naloxone is an opioid-receptor antagonist. In other words, it has the ability to displace an opioid from the receptor site, and essentially reverse its activity to save overdose victims. However, a significant increase in the cost of naloxone has put it out of reach of the people who need it most…. These price increases came when the opioid epidemic was at its peak, and they came without any explanation. There have been actions in several states to limit these increases, but little in the way of federal regulation to enforce them, despite recommendations by the CDC to expand access.